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One small study reported positive outcomes with intra-articular BPC 157 injections for knee osteoarthritis, but the sample size was limited (PMID: 34324435)

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291 For instance, studies have pointed out that environmental exposure to silica NPs can cause the ROS-mediated autophagy dysfunction and cell apoptosis through MAPK/Bcl-2 and PI3K/Akt/mTOR signaling pathways